The erk pathway plays an important role of integrating external signals from the presence of mitogens such as epidermal growth factor (egf) into signaling events promoting cell growth. The erk/mapk signaling pathway transmits signals from the cell surface to the nucleus. Feb 10, 2026explore the erk pathway and its role in cell proliferation and survival.
Jun 23, 2020by phosphorylating widely diverse substrates, erk proteins govern a variety of evolutionarily conserved cellular processes in metazoans, the dysregulation of which. Extracellular signal-regulated kinase (erk) is a member of the mitogen-activated protein kinase family of signaling molecules. Erk is predominantly found in two forms, erk1 (p44) and erk2.
Dec 1, 2023extracellular signal-regulated kinase (erk) has long been studied as a key driver of both essential cellular processes and disease. Nov 10, 2023in this review, we will document key in vivo and in vitro examples that have established a clear link between cell deformation, mechanical stress and modulation of erk.
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